Both itineraries offer very different, but equally breathtaking, attractions.
What you should do depends on what you want to do. Is it hiking? Discovering ancient ruins? Relaxing on a beach? Exploring the Amazon?
You can download my free '
Attractions of South America' ebook. Maybe it'll help you decide where you'd like to go.
Don't forget South America is huge. Distances are enormous. You'll spend lots of time in buses if you travel overland.
The itinerary on your map is going to take you months, my guess would be a trip of 6 months, if you want to do it without rushing. Again, distances are enormous. You'll be crossing The Andes to the Amazon Basin. I see on your map that you'd like to travel from Potosi to Brazil. You can only enter Brazil in Guayaramerin. Getting there overland is going to take you weeks. Have a look at my
Amazon river boat story that took me from Trinidad (Bolivia) all the way to Brazil (unforgettable experience).
As always, how long you'll stay at a place all depends on how much you're enjoying yourself.
Have fun! Keep us posted!